effect of oxytocin on hisological structure and mitotic index of spleen in albino mice

The aimed of these research to shed some light on the effects of oxyticin in histological structure for spleer in male albino mice at age of four and five weeke, the animals were injected intra peritonealy at a dose of 0.2 ml. The results showed some histological changes in spleen, the blood vessels demonstrated vasodilation and fractionation which caused hemorrhage. The lymphoid tissue in periarterial lymphatic sheath [PALS] region of splenic nodule and in red pulp was loose and hyperplasia was present represented by blood vessel congestion and increasing in the number of phagocytes, plasma cells and giant cells and also theme was a significant elevation in the value of spleens cells mitotic Index which was seen in red and white pulp